7KP4

Crystal structure of human claudin-4 in complex with Clostridium perfringens enterotoxin C-terminal domain

7KP4 の概要

• エントリーDOI: 10.2210/pdb7kp4/pdb
• 分子名称: Claudin-4, Heat-labile enterotoxin B chain (2 entities in total)
• 機能のキーワード: claudin, enterotoxin, tight junction protein, transmembrane protein, cell adhesion-toxin complex, cell adhesion/toxin
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37728.80

構造登録者

Vecchio, A.J.,Stroud, R.M. (登録日: 2020-11-10, 公開日: 2020-12-09, 最終更新日: 2023-10-18)

• 主引用文献: Vecchio, A.J.,Rathnayake, S.S.,Stroud, R.M.; Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gut.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33876770; DOI: 10.1073/pnas.2024651118

実験手法

X-RAY DIFFRACTION (3.37 Å)