7KNF

1.80A resolution structure of independent Phosphoglycerate mutase from C. elegans in complex with a macrocyclic peptide inhibitor (Ce-1 NHOH)

Summary for 7KNF

Entry DOI	10.2210/pdb7knf/pdb
Descriptor	2,3-bisphosphoglycerate-independent phosphoglycerate mutase, DTY-ASP-TYR-PRO-GLY-ASP-HIS-CYS-TYR-LEU-TYR-GLY-THR, ZINC ION, ... (6 entities in total)
Functional Keywords	phosphoglycerate mutase, ipglycermide, peptide inhibitors, metal ion binding, isomerase
Biological source	Caenorhabditis elegans More
Total number of polymer chains	4
Total formula weight	122731.89
Authors	Lovell, S.,Kashipathy, M.M.,Battaile, K.P.,Weidmann, M.,Dranchak, P.,Aitha, M.,Queme, B.,Collmus, C.D.,Kanter, L.,Lamy, L.,Tao, D.,Rai, G.,Suga, H.,Inglese, J. (deposition date: 2020-11-04, release date: 2021-04-07, Last modification date: 2023-11-15)
Primary citation	Wiedmann, M.,Dranchak, P.K.,Aitha, M.,Queme, B.,Collmus, C.D.,Kashipathy, M.M.,Kanter, L.,Lamy, L.,Rogers, J.M.,Tao, D.,Battaile, K.P.,Rai, G.,Lovell, S.,Suga, H.,Inglese, J. Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases. J.Biol.Chem., 296:100628-100628, 2021 Cited by PubMed: 33812994 DOI: 10.1016/j.jbc.2021.100628 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation