7KLI

Crystal Structure of Enoyl-[acyl-carrier-protein] reductase [NADH] (InhA) from Mycobacterium abscessus

7KLI の概要

• エントリーDOI: 10.2210/pdb7kli/pdb
• 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], 1,2-ETHANEDIOL, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: ssgcid, enoyl-[acyl-carrier-protein] reductase, inha, mab_2722c, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase
• 由来する生物種: Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 119921.21

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2020-10-30, 公開日: 2020-11-11, 最終更新日: 2023-10-18)

• 主引用文献: Alcaraz, M.,Roquet-Baneres, F.,Leon-Icaza, S.A.,Abendroth, J.,Boudehen, Y.M.,Cougoule, C.,Edwards, T.E.,Kremer, L.; Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA.; Acs Infect Dis., 8:2171-2186, 2022; PubMed: 36107992; DOI: 10.1021/acsinfecdis.2c00314

実験手法