7KL5
Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues: Phe4246 to Val4271
Summary for 7KL5
Entry DOI | 10.2210/pdb7kl5/pdb |
Descriptor | Calmodulin-1, Ryanodine receptor 2, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | calmodulin, cam, ryr2, cam binding domain, ryanodine receptor, metal binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 20953.91 |
Authors | Fisher, A.J.,Ames, J.B.,Yu, Q. (deposition date: 2020-10-29, release date: 2021-04-07, Last modification date: 2023-10-18) |
Primary citation | Yu, Q.,Anderson, D.E.,Kaur, R.,Fisher, A.J.,Ames, J.B. The Crystal Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues Phe4246-Val4271 Reveals a Fifth Calcium Binding Site. Biochemistry, 60:1088-1096, 2021 Cited by PubMed: 33754699DOI: 10.1021/acs.biochem.1c00152 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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