7KJM

CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH D-PEPTIDE INHIBITOR (DPMI-OMEGA)

7KJM の概要

• エントリーDOI: 10.2210/pdb7kjm/pdb
• 関連するBIRD辞書のPRD_ID: PRD_002455
• 分子名称: E3 ubiquitin-protein ligase Mdm2, D-PMI-omega, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• 機能のキーワード: mdm2, p53 binding domain, d-peptide activator of mdm2, mdm2-d-peptide complex, host-virus interaction, ligase, metal-binding, nucleus, phosphoprotein, proto-oncogene, ubl conjugation pathway, zinc-finger, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 23715.59

構造登録者

Tolbert, W.D.,Pazgier, M. (登録日: 2020-10-26, 公開日: 2021-11-17, 最終更新日: 2023-11-15)

• 主引用文献: Tolbert, W.D.,Pazgier, M.; CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH D-PEPTIDE INHIBITOR (DPMI-OMEGA); To Be Published,

実験手法

X-RAY DIFFRACTION (1.4 Å)