7KJA
Crystal structure of the EphA2 intracellular KD-SAM domains
Summary for 7KJA
Entry DOI | 10.2210/pdb7kja/pdb |
Descriptor | Ephrin type-A receptor 2, GLYCEROL, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (5 entities in total) |
Functional Keywords | eph receptor, kinase, sam, allostery, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 89412.43 |
Authors | Lechtenberg, B.C.,Pasquale, E.B. (deposition date: 2020-10-26, release date: 2021-02-03, Last modification date: 2023-10-18) |
Primary citation | Lechtenberg, B.C.,Gehring, M.P.,Light, T.P.,Horne, C.R.,Matsumoto, M.W.,Hristova, K.,Pasquale, E.B. Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker. Nat Commun, 12:7047-7047, 2021 Cited by PubMed: 34857764DOI: 10.1038/s41467-021-27343-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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