7KJ2

SARS-CoV-2 Spike Glycoprotein with one ACE2 Bound

Summary for 7KJ2

EMDB information22891
DescriptorSpike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordsviral protein, viral protein-hydrolase complex, viral protein/hydrolase
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains4
Total molecular weight495882.83
Authors
Zhang, J.,Xiao, T.S.,Cai, Y.F.,Chen, B. (deposition date: 2020-10-25, release date: 2020-11-11)
Primary citation
Xiao, T.,Lu, J.,Zhang, J.,Johnson, R.I.,McKay, L.G.A.,Storm, N.,Lavine, C.L.,Peng, H.,Cai, Y.,Rits-Volloch, S.,Lu, S.,Quinlan, B.D.,Farzan, M.,Seaman, M.S.,Griffiths, A.,Chen, B.
A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent in vitro.
Biorxiv, 2020
PubMed: 32995768 (PDB entries with the same primary citation)
DOI: 10.1101/2020.09.18.301952
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers7 0.5% 1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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171588
PDB entries from 2020-11-25