7KI7

The external aldimine crystal structure of the beta-K167T mutant Tryptophan Synthase at 1.75 Angstrom resolution in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site

Summary for 7KI7

• Entry DOI: 10.2210/pdb7ki7/pdb
• Related: 6DZ4 6DZO 6SXY 7JMQ 7JQW 7JTT 7K5A
• Descriptor: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (10 entities in total)
• Functional Keywords: inhibitor, external aldimine, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 73577.68

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-10-23, release date: 2021-10-27, Last modification date: 2023-10-18)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The external aldimine crystal structure of the beta-K167T mutant Tryptophan Synthase at 1.75 Angstrom resolution in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)