7KH9
Crystal structure of OXA-48 K73A in complex with imipenem
Summary for 7KH9
Entry DOI | 10.2210/pdb7kh9/pdb |
Descriptor | Beta-lactamase, (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | beta-lactamase, carbapenemase, beta-lactamase inhibitor, complex, oxacillinase, hydrolase, hydrolase-hydrolase inhibitor complex |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 57132.43 |
Authors | Palzkill, T.,Hu, L.,Sankaran, B.,Prasad, B.V.V. (deposition date: 2020-10-20, release date: 2021-02-10, Last modification date: 2023-10-18) |
Primary citation | Stojanoski, V.,Hu, L.,Sankaran, B.,Wang, F.,Tao, P.,Prasad, B.V.V.,Palzkill, T. Mechanistic Basis of OXA-48-like beta-Lactamases' Hydrolysis of Carbapenems. Acs Infect Dis., 7:445-460, 2021 Cited by PubMed: 33492952DOI: 10.1021/acsinfecdis.0c00798 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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