7KH4

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56W mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site

Summary for 7KH4

• Entry DOI: 10.2210/pdb7kh4/pdb
• Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, MAGNESIUM ION, ... (10 entities in total)
• Functional Keywords: dihydrodipicolinate synthase, lyase
• Biological source: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
• Total number of polymer chains: 6
• Total formula weight: 212552.11

Authors

Saran, S.,Majdi Yazdi, M.,Sanders, D.A.R. (deposition date: 2020-10-19, release date: 2021-10-27, Last modification date: 2023-11-29)

• Primary citation: Majdi Yazd, M.,Reddy Annadi, K.,Saran, S.,Bhagwat, A.,Sanders, D.A.R.,Palmer, D.R.J.; Fluorescence-based Assay Development for Screening Novel Inhibitors of Dihydrodipicolinate Synthase from Campylobacter jejuni; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)