7KFZ
Structure of a ternary KRas(G13D)-SOS complex
Summary for 7KFZ
Entry DOI | 10.2210/pdb7kfz/pdb |
EMDB information | 22857 |
Descriptor | GTPase KRas, Son of sevenless homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total) |
Functional Keywords | ras, sos, gtpase, hydrolase-signaling protein complex, hydrolase/signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 96769.89 |
Authors | Liu, C.,Moghadamchargari, Z.,Laganowsky, A.,Zhao, M. (deposition date: 2020-10-15, release date: 2021-03-31, Last modification date: 2024-03-06) |
Primary citation | Moghadamchargari, Z.,Shirzadeh, M.,Liu, C.,Schrecke, S.,Packianathan, C.,Russell, D.H.,Zhao, M.,Laganowsky, A. Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33723061DOI: 10.1073/pnas.2022403118 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.47 Å) |
Structure validation
Download full validation report