7KFK

Crystal structure of LILRB1 D3D4 domain in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain

7KFK の概要

• エントリーDOI: 10.2210/pdb7kfk/pdb
• 分子名称: Isoform 2 of Leukocyte immunoglobulin-like receptor subfamily B member 1, Rifin, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: lilrb1, rifin, malaria, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 83370.93

構造登録者

Xu, K.,Kwong, P.D. (登録日: 2020-10-14, 公開日: 2021-03-31, 最終更新日: 2023-10-18)

• 主引用文献: Chen, Y.,Xu, K.,Piccoli, L.,Foglierini, M.,Tan, J.,Jin, W.,Gorman, J.,Tsybovsky, Y.,Zhang, B.,Traore, B.,Silacci-Fregni, C.,Daubenberger, C.,Crompton, P.D.,Geiger, R.,Sallusto, F.,Kwong, P.D.,Lanzavecchia, A.; Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.; Nature, 592:639-643, 2021; PubMed: 33790470; DOI: 10.1038/s41586-021-03378-6

実験手法

X-RAY DIFFRACTION (2.63 Å)