7KDY
Crystal structure of Streptomyces tokunonesis TokK with hydroxycobalamin, 5'-deoxyadenosine, methionine, and (2R)-pantetheinylated carbapenam
Summary for 7KDY
Entry DOI | 10.2210/pdb7kdy/pdb |
Descriptor | Methyltransferase TokK, IRON/SULFUR CLUSTER, COBALAMIN, ... (9 entities in total) |
Functional Keywords | radical sam, cobalamin, [4fe-4s] cluster, fes cluster, methyltransferase, b12, beta-lactam antibiotic synthesis, transferase |
Biological source | Streptomyces tokunonensis |
Total number of polymer chains | 2 |
Total formula weight | 159854.23 |
Authors | Knox, H.L.,Booker, S.J.,Boal, A.K. (deposition date: 2020-10-09, release date: 2022-01-12, Last modification date: 2024-04-03) |
Primary citation | Knox, H.L.,Sinner, E.K.,Townsend, C.A.,Boal, A.K.,Booker, S.J. Structure of a B 12 -dependent radical SAM enzyme in carbapenem biosynthesis. Nature, 602:343-348, 2022 Cited by PubMed: 35110734DOI: 10.1038/s41586-021-04392-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.939 Å) |
Structure validation
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