7KC6

X-ray structure of Lfa-1 I domain in complex with Lovastatin collected at 273 K

Summary for 7KC6

• Entry DOI: 10.2210/pdb7kc6/pdb
• Related: 7KC3 7KC5
• Descriptor: Integrin alpha-L, LOVASTATIN, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: integrin, adhesion, cell adhesion
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 42729.64

Authors

Woldeyes, R.A.,Hallenbeck, K.K.,Pfaff, S.J.,Lee, G.,Cortez, S.V.,Kelly, M.J.,Akassoglou, K.,Arkin, M.R.,Fraser, J.S. (deposition date: 2020-10-05, release date: 2021-10-06, Last modification date: 2023-10-18)

• Primary citation: Woldeyes, R.A.,Hallenbeck, K.K.,Pfaff, S.J.,Lee, G.,Cortez, S.V.,Kelly, M.J.,Akassoglou, K.,Arkin, M.R.,Fraser, J.S.; Divergent conformational dynamics controls allosteric ligand accessibility across evolutionarily related I-domain-containing integrins; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)