7KA1

1.60 Angstrom resolution crystal structure of the beta-Q114A mutant Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and cesium ion at the metal coordination site

7KA1 の概要

• エントリーDOI: 10.2210/pdb7ka1/pdb
• 関連するPDBエントリー: 4HN4 4HPX 6D0V 6X0C
• 分子名称: Tryptophan synthase alpha chain, DI(HYDROXYETHYL)ETHER, Tryptophan synthase beta chain, ... (11 entities in total)
• 機能のキーワード: lyase, inhibitor, tryptophan synthase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74749.13

構造登録者

Hilario, E.,Dunn, M.F.,Mueller, L.J. (登録日: 2020-09-29, 公開日: 2021-09-29, 最終更新日: 2023-10-18)

• 主引用文献: Hilario, E.,Dunn, M.F.,Mueller, L.J.; 1.60 Angstrom resolution crystal structure of the beta-Q114A mutant Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and cesium ion at the metal coordination site.; To be Published,

実験手法

X-RAY DIFFRACTION (1.6 Å)