7K6A
Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001575
7K6A の概要
エントリーDOI | 10.2210/pdb7k6a/pdb |
分子名称 | Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6-ethyl-5-[3-({3-[4-(trifluoromethyl)piperidin-1-yl]pyridin-2-yl}oxy)propoxy]pyrimidine-2,4-diamine, ... (6 entities in total) |
機能のキーワード | ssgcid, sddc, inhibitor, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
由来する生物種 | Mycobacterium ulcerans (strain Agy99) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 20457.21 |
構造登録者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2020-09-19, 公開日: 2021-03-17, 最終更新日: 2023-10-18) |
主引用文献 | Abendroth, J.,Dranow, D.M.,Santhakumar, V.,Walpole, C.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E. Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001575 to be published, |
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