7K62
Crystal Structure of Dihydrofolate reductase from Mycobacterium kansasii in complex with NADP and inhibitor P218
7K62 の概要
エントリーDOI | 10.2210/pdb7k62/pdb |
分子名称 | Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, ... (5 entities in total) |
機能のキーワード | ssgcid, tetrahydrofolate biosynthesis, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
由来する生物種 | Mycobacterium kansasii |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 39805.80 |
構造登録者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2020-09-18, 公開日: 2021-03-17, 最終更新日: 2023-10-18) |
主引用文献 | Abendroth, J.,Dranow, D.M.,Santhakumar, V.,Walpole, C.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E. Crystal Structure of Dihydrofolate reductase from Mycobacterium kansasii in complex with NADP and inhibitor P218 To Be Published, |
実験手法 | X-RAY DIFFRACTION (2.05 Å) |
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