7K4Y
Crystal structure of Kemp Eliminase HG3.17 at 343 K
Summary for 7K4Y
Entry DOI | 10.2210/pdb7k4y/pdb |
Descriptor | Endo-1,4-beta-xylanase (2 entities in total) |
Functional Keywords | kemp elimination, directed evolution, high temperature, multiple conformations, hydrolase |
Biological source | Thermoascus aurantiacus |
Total number of polymer chains | 1 |
Total formula weight | 33176.43 |
Authors | Padua, R.A.P.,Otten, R.,Bunzel, A.,Nguyen, V.,Pitsawong, W.,Patterson, M.,Sui, S.,Perry, S.L.,Cohen, A.E.,Hilvert, D.,Kern, D. (deposition date: 2020-09-16, release date: 2020-12-02, Last modification date: 2023-10-18) |
Primary citation | Otten, R.,Padua, R.A.P.,Bunzel, H.A.,Nguyen, V.,Pitsawong, W.,Patterson, M.,Sui, S.,Perry, S.L.,Cohen, A.E.,Hilvert, D.,Kern, D. How directed evolution reshapes the energy landscape in an enzyme to boost catalysis. Science, 370:1442-1446, 2020 Cited by PubMed: 33214289DOI: 10.1126/science.abd3623 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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