7K4Y

Crystal structure of Kemp Eliminase HG3.17 at 343 K

Summary for 7K4Y

Entry DOI	10.2210/pdb7k4y/pdb
Descriptor	Endo-1,4-beta-xylanase (2 entities in total)
Functional Keywords	kemp elimination, directed evolution, high temperature, multiple conformations, hydrolase
Biological source	Thermoascus aurantiacus
Total number of polymer chains	1
Total formula weight	33176.43
Authors	Padua, R.A.P.,Otten, R.,Bunzel, A.,Nguyen, V.,Pitsawong, W.,Patterson, M.,Sui, S.,Perry, S.L.,Cohen, A.E.,Hilvert, D.,Kern, D. (deposition date: 2020-09-16, release date: 2020-12-02, Last modification date: 2023-10-18)
Primary citation	Otten, R.,Padua, R.A.P.,Bunzel, H.A.,Nguyen, V.,Pitsawong, W.,Patterson, M.,Sui, S.,Perry, S.L.,Cohen, A.E.,Hilvert, D.,Kern, D. How directed evolution reshapes the energy landscape in an enzyme to boost catalysis. Science, 370:1442-1446, 2020 Cited by PubMed: 33214289 DOI: 10.1126/science.abd3623 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation