7K1D

Crystal structure of human insulin degrading enzyme (IDE) in complex with compound BDM_77291

Summary for 7K1D

• Entry DOI: 10.2210/pdb7k1d/pdb
• Descriptor: Insulin-degrading enzyme, ZINC ION, (3R)-3-{4-[(3R)-4-(3,4-difluorobenzene-1-carbonyl)morpholin-3-yl]-1H-1,2,3-triazol-1-yl}-N-hydroxy-4-(naphthalen-2-yl)butanamide, ... (5 entities in total)
• Functional Keywords: hydrolase, inhibitor, hydrolase-hydrolase inhbitor complex, hydrolase/hydrolase inhbitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 231302.21

Authors

Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W. (deposition date: 2020-09-07, release date: 2021-09-22, Last modification date: 2023-10-18)

• Primary citation: Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W.; Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 2; To Be Published,

Experimental method

X-RAY DIFFRACTION (3 Å)