7K1B
CryoEM structure of DNA-PK catalytic subunit complexed with DNA (Complex II)
Summary for 7K1B
Entry DOI | 10.2210/pdb7k1b/pdb |
Related | 7K11 7K19 |
EMDB information | 22620 22622 22623 |
Descriptor | DNA-dependent protein kinase catalytic subunit, DNA (5'-D(P*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), DNA (5'-D(P*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*AP*TP*GP*C)-3') (3 entities in total) |
Functional Keywords | nhej, v(d)j recombination, dna repair, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 489252.89 |
Authors | Chen, X.,Gellert, M.,Yang, W. (deposition date: 2020-09-07, release date: 2021-01-06, Last modification date: 2024-03-06) |
Primary citation | Chen, X.,Xu, X.,Chen, Y.,Cheung, J.C.,Wang, H.,Jiang, J.,de Val, N.,Fox, T.,Gellert, M.,Yang, W. Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81:801-810.e3, 2021 Cited by PubMed: 33385326DOI: 10.1016/j.molcel.2020.12.015 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.3 Å) |
Structure validation
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