7K0A

Puromycin N-acetyltransferase in complex with acetylated puromycin and CoA

7K0A の概要

• エントリーDOI: 10.2210/pdb7k0a/pdb
• 分子名称: Puromycin N-acetyltransferase, N-Acetylpuromycin, COENZYME A, ... (7 entities in total)
• 機能のキーワード: enzyme acetyletransferase complex selection marker, antibiotic, transferase
• 由来する生物種: Streptomyces alboniger
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48699.96

構造登録者

Peat, T.S.,Caputo, A.T.,Newman, J.,Adams, T.E. (登録日: 2020-09-03, 公開日: 2021-03-17, 最終更新日: 2023-10-18)

• 主引用文献: Caputo, A.T.,Eder, O.M.,Bereznakova, H.,Pothuis, H.,Ardevol, A.,Newman, J.,Nuttall, S.,Peat, T.S.,Adams, T.E.; Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.; Sci Rep, 11:5247-5247, 2021; PubMed: 33664348; DOI: 10.1038/s41598-021-84551-9

実験手法

X-RAY DIFFRACTION (2 Å)