7JY5
Structure of human p97 in complex with ATPgammaS and Npl4/Ufd1 (masked around p97)
Summary for 7JY5
Entry DOI | 10.2210/pdb7jy5/pdb |
EMDB information | 21824 21825 21826 22521 |
Descriptor | Transitional endoplasmic reticulum ATPase, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total) |
Functional Keywords | aaa+ atpase chaperon protein homeostasis, translocase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 543191.54 |
Authors | |
Primary citation | Pan, M.,Zheng, Q.,Yu, Y.,Ai, H.,Xie, Y.,Zeng, X.,Wang, C.,Liu, L.,Zhao, M. Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative. Nat Commun, 12:121-121, 2021 Cited by PubMed: 33402676DOI: 10.1038/s41467-020-20359-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.89 Å) |
Structure validation
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