7JV4

SARS-CoV-2 spike in complex with the S2H13 neutralizing antibody (one RBD open)

Summary for 7JV4

EMDB information22492 22491 22494 22497 22506 22507 22508
DescriptorSARS-CoV-2 spike glycoprotein, S2H13 Fab heavy chain, S2H13 Fab light chain, ... (5 entities in total)
Functional Keywordssars-cov-2, covid-19, spike glycoprotein, fusion protein, neutralizing antibodies, viral protein-immune system complex, viral protein/immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains9
Total molecular weight511070.03
Authors
Primary citation
Piccoli, L.,Park, Y.J.,Tortorici, M.A.,Czudnochowski, N.,Walls, A.C.,Beltramello, M.,Silacci-Fregni, C.,Pinto, D.,Rosen, L.E.,Bowen, J.E.,Acton, O.J.,Jaconi, S.,Guarino, B.,Minola, A.,Zatta, F.,Sprugasci, N.,Bassi, J.,Peter, A.,De Marco, A.,Nix, J.C.,Mele, F.,Jovic, S.,Rodriguez, B.F.,Gupta, S.V.,Jin, F.,Piumatti, G.,Lo Presti, G.,Pellanda, A.F.,Biggiogero, M.,Tarkowski, M.,Pizzuto, M.S.,Cameroni, E.,Havenar-Daughton, C.,Smithey, M.,Hong, D.,Lepori, V.,Albanese, E.,Ceschi, A.,Bernasconi, E.,Elzi, L.,Ferrari, P.,Garzoni, C.,Riva, A.,Snell, G.,Sallusto, F.,Fink, K.,Virgin, H.W.,Lanzavecchia, A.,Corti, D.,Veesler, D.
Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
PubMed: 32991844 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2020.09.037
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers00 0.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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169963
PDB entries from 2020-10-14