7JTC

Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-322

Summary for 7JTC

• Entry DOI: 10.2210/pdb7jtc/pdb
• Descriptor: Transcription initiation factor TFIID subunit 1, 1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(methylsulfanyl)pyrimidin-4-yl}cyclopropane-1-sulfonimidoamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: bromodomain, taf1, non-bet, bet, kinase inhibitor, atr, dual brd-kinase, gene regulation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16350.42

Authors

Karim, M.R.,Schonbrunn, E. (deposition date: 2020-08-17, release date: 2021-08-25, Last modification date: 2023-10-18)

• Primary citation: Karim, M.R.,Schonbrunn, E.; Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-322; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)