7JSE
Adeno-Associated Virus Origin Binding Domain in complex with ssDNA
Summary for 7JSE
Entry DOI | 10.2210/pdb7jse/pdb |
EMDB information | 22451 |
Descriptor | Protein Rep68, DNA (5'-D(*TP*TP*TP*T)-3') (2 entities in total) |
Functional Keywords | aav, protein-dna, aaa+, sf3, huh, viral protein, viral protein-dna complex, viral protein/dna |
Biological source | Adeno-associated virus - 2 (AAV-2) More |
Total number of polymer chains | 24 |
Total formula weight | 984459.14 |
Authors | Escalante, C.R. (deposition date: 2020-08-14, release date: 2020-12-09, Last modification date: 2024-05-29) |
Primary citation | Santosh, V.,Musayev, F.N.,Jaiswal, R.,Zarate-Perez, F.,Vandewinkel, B.,Dierckx, C.,Endicott, M.,Sharifi, K.,Dryden, K.,Henckaerts, E.,Escalante, C.R. The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states. Nucleic Acids Res., 48:12983-12999, 2020 Cited by PubMed: 33270897DOI: 10.1093/nar/gkaa1133 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.6 Å) |
Structure validation
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