7JS5

Phospholipase D engineered mutant (TNYR) inactive enzyme (H168A) bound to 1-inositol phosphate

7JS5 の概要

• エントリーDOI: 10.2210/pdb7js5/pdb
• 分子名称: Phospholipase D, D-MYO-INOSITOL-1-PHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total)
• 機能のキーワード: engineered mutant, pseudo-dimeric architecture, myo-inositol specificity, lipid binding protein
• 由来する生物種: Streptomyces antibioticus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54394.29

構造登録者

Vrielink, A.,Samantha, A. (登録日: 2020-08-13, 公開日: 2021-04-28, 最終更新日: 2023-10-18)

• 主引用文献: Samantha, A.,Damnjanovic, J.,Iwasaki, Y.,Nakano, H.,Vrielink, A.; Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation.; Biochem.J., 478:1749-1767, 2021; PubMed: 33843991; DOI: 10.1042/BCJ20210117

実験手法

X-RAY DIFFRACTION (2.5 Å)