7JME
Structure of the SARS-CoV-2 NSP3 Macro X domain in complex with cyclic AMP
Summary for 7JME
Entry DOI | 10.2210/pdb7jme/pdb |
Descriptor | Non-structural protein 3, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | macro domain, camp, cyclic amp, viral protein, sars-cov-2, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus) |
Total number of polymer chains | 1 |
Total formula weight | 18823.31 |
Authors | Vuksanovic, N.,Melkonian, T.R.,Silvaggi, N.R. (deposition date: 2020-07-31, release date: 2020-09-02, Last modification date: 2023-10-18) |
Primary citation | Virdi, R.S.,Bavisotto, R.V.,Hopper, N.C.,Vuksanovic, N.,Melkonian, T.R.,Silvaggi, N.R.,Frick, D.N. Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3. Slas Discov, 25:1162-1170, 2020 Cited by PubMed: 32981460DOI: 10.1177/2472555220960428 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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