7JME

Structure of the SARS-CoV-2 NSP3 Macro X domain in complex with cyclic AMP

7JME の概要

• エントリーDOI: 10.2210/pdb7jme/pdb
• 分子名称: Non-structural protein 3, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: macro domain, camp, cyclic amp, viral protein, sars-cov-2, viral protein-inhibitor complex, viral protein/inhibitor
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18823.31

構造登録者

Vuksanovic, N.,Melkonian, T.R.,Silvaggi, N.R. (登録日: 2020-07-31, 公開日: 2020-09-02, 最終更新日: 2023-10-18)

• 主引用文献: Virdi, R.S.,Bavisotto, R.V.,Hopper, N.C.,Vuksanovic, N.,Melkonian, T.R.,Silvaggi, N.R.,Frick, D.N.; Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3.; Slas Discov, 25:1162-1170, 2020; PubMed: 32981460; DOI: 10.1177/2472555220960428

実験手法

X-RAY DIFFRACTION (1.55 Å)