7JLP

cryo-EM structure of human ATG9A in nanodiscs

Summary for 7JLP

• Entry DOI: 10.2210/pdb7jlp/pdb
• EMDB information: 22375 22376 22377
• Descriptor: Autophagy-related protein 9A, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (2 entities in total)
• Functional Keywords: autophagy, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 234595.45

Authors

Maeda, S.,Otomo, T. (deposition date: 2020-07-30, release date: 2020-10-28, Last modification date: 2020-12-16)

• Primary citation: Maeda, S.,Yamamoto, H.,Kinch, L.N.,Garza, C.M.,Takahashi, S.,Otomo, C.,Grishin, N.V.,Forli, S.,Mizushima, N.,Otomo, T.; Structure, lipid scrambling activity and role in autophagosome formation of ATG9A.; Nat.Struct.Mol.Biol., 27:1194-1201, 2020; PubMed: 33106659; DOI: 10.1038/s41594-020-00520-2

Experimental method

ELECTRON MICROSCOPY (3.4 Å)