Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7JJL

Crystal structure of Importin Alpha 3 in complex with human LSD1 NLS

Summary for 7JJL
Entry DOI10.2210/pdb7jjl/pdb
DescriptorImportin subunit alpha-3, Lysine-specific histone demethylase 1A (3 entities in total)
Functional Keywordsdemethylase importin alpha, protein transport
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight54265.19
Authors
Primary citationTu, W.J.,McCuaig, R.D.,Tan, A.H.Y.,Hardy, K.,Seddiki, N.,Ali, S.,Dahlstrom, J.E.,Bean, E.G.,Dunn, J.,Forwood, J.,Tsimbalyuk, S.,Smith, K.,Yip, D.,Malik, L.,Prasanna, T.,Milburn, P.,Rao, S.
Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch.
Front Immunol, 11:1228-, 2020
Cited by
PubMed: 32612611
DOI: 10.3389/fimmu.2020.01228
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

217705

数据于2024-03-27公开中

PDB statisticsPDBj update infoContact PDBjnumon