7JHN

Structure of human beta 1,3-N-acetylglucosaminyltransferase 2 with UDP and trisaccharide GlcNAc-beta1-3Gal-beta1-4GlcNAc

7JHN の概要

• エントリーDOI: 10.2210/pdb7jhn/pdb
• 分子名称: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: glycosyltransferase, poly-n-acetyl-lactosamine, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45518.20

構造登録者

Hao, Y.,Huang, X. (登録日: 2020-07-21, 公開日: 2020-11-18, 最終更新日: 2023-10-18)

• 主引用文献: Hao, Y.,Crequer-Grandhomme, A.,Javier, N.,Singh, A.,Chen, H.,Manzanillo, P.,Lo, M.C.,Huang, X.; Structures and mechanism of human glycosyltransferase beta 1,3-N-acetylglucosaminyltransferase 2 (B3GNT2), an important player in immune homeostasis.; J.Biol.Chem., 296:100042-100042, 2020; PubMed: 33158990; DOI: 10.1074/jbc.RA120.015306

実験手法

X-RAY DIFFRACTION (2.2 Å)