7JHJ

Structure of the Epstein-Barr virus GPCR BILF1 in complex with human Gi

7JHJ の概要

• エントリーDOI: 10.2210/pdb7jhj/pdb
• EMDBエントリー: 22338
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: membrane protein, viral gpcr, class a-like gpcr, epstein-barr virus
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 148763.61

構造登録者

Tsutsumi, N.,Qu, Q.H.,Skiniotis, G.,Garcia, K.C. (登録日: 2020-07-20, 公開日: 2021-07-07, 最終更新日: 2021-07-28)

• 主引用文献: Tsutsumi, N.,Qu, Q.,Mavri, M.,Baggesen, M.S.,Maeda, S.,Waghray, D.,Berg, C.,Kobilka, B.K.,Rosenkilde, M.M.,Skiniotis, G.,Garcia, K.C.; Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1.; Immunity, 54:1405-1416.e7, 2021; PubMed: 34216564; DOI: 10.1016/j.immuni.2021.06.001

実験手法

ELECTRON MICROSCOPY (3.2 Å)