7JGI
NMR structure of the cNTnC-cTnI chimera bound to A7
Summary for 7JGI
Entry DOI | 10.2210/pdb7jgi/pdb |
NMR Information | BMRB: 30774 |
Descriptor | Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle chimera, CALCIUM ION, 7-{[(5-chloronaphthalen-1-yl)sulfonyl]amino}heptanoic acid (3 entities in total) |
Functional Keywords | cardiac troponin, calcium binding protein, ef hand, metal binding protein, calcium modulator |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 14596.07 |
Authors | Cai, F.,Robertson, I.M.,Kampourakis, T.,Klein, B.A.,Sykes, B.D. (deposition date: 2020-07-19, release date: 2020-09-02, Last modification date: 2024-05-15) |
Primary citation | Cai, F.,Robertson, I.M.,Kampourakis, T.,Klein, B.A.,Sykes, B.D. The Role of Electrostatics in the Mechanism of Cardiac Thin Filament Based Sensitizers. Acs Chem.Biol., 15:2289-2298, 2020 Cited by PubMed: 32633482DOI: 10.1021/acschembio.0c00519 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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