7I8J

Crystal Structure of 61g bound to CK2a

This is a non-PDB format compatible entry.

Summary for 7I8J

• Entry DOI: 10.2210/pdb7i8j/pdb
• Group deposition: the group title you wish to show (G_1002301)
• Descriptor: Casein kinase II subunit alpha, 5-{2-[4-({[4-chloro-3-(trifluoromethoxy)phenyl]methyl}amino)butoxy]ethoxy}benzo[c][2,6]naphthyridine-8-carboxylic acid (3 entities in total)
• Functional Keywords: fragment based drug discovery, kinase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39595.34

Authors

Brear, P.,Glossop, P.,Pandey, S.,Hyvonen, M.,Spring, D.,Butt, R.,Cawkill, D. (deposition date: 2025-03-12, release date: 2026-01-14)

• Primary citation: Glossop, P.,Brear, P.,Pandey, S.,Hyvonen, M.,Spring, D.,Butt, R.,Cawkill, D.; Anti-tumor Efficacy of CK2a; inhibition in Wnt-Driven Colorectal Cancer; To be published,

Experimental method

X-RAY DIFFRACTION (1.598 Å)