7I2I

Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 -- Crystal structure of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 in complex with Z1262628644 (DNV2_NS5A-x0472)

This is a non-PDB format compatible entry.

Summary for 7I2I

• Entry DOI: 10.2210/pdb7i2i/pdb
• Group deposition: Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 (G_1002341)
• Descriptor: NS5 RNA-dependent RNA polymerase, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (9 entities in total)
• Functional Keywords: diamond light source, i04-1, readdi, dengue virus, crystallographic fragment screening, pandda, xchemexplorer, cluster4x, viral protein
• Biological source: dengue virus type 2
• Total number of polymer chains: 1
• Total formula weight: 75022.22

Authors

Aschenbrenner, J.C.,Saini, M.,Chopra, A.,Marples, P.G.,Balcomb, B.H.,Lithgo, R.M.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E. (deposition date: 2025-03-06, release date: 2025-04-02, Last modification date: 2026-02-18)

• Primary citation: Aschenbrenner, J.C.,Saini, M.,Chopra, A.,Marples, P.G.,Balcomb, B.H.,Lithgo, R.M.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E.; Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.74 Å)