7I2H

Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 -- Crystal structure of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 in complex with Z1198177230 (DNV2_NS5A-x0411)

Summary for 7I2H

Entry DOI	10.2210/pdb7i2h/pdb
Group deposition	Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 (G_1002341)
Descriptor	NS5 RNA-dependent RNA polymerase, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (9 entities in total)
Functional Keywords	diamond light source, i04-1, readdi, dengue virus, crystallographic fragment screening, pandda, xchemexplorer, cluster4x, viral protein
Biological source	dengue virus type 2
Total number of polymer chains	1
Total formula weight	75134.32
Authors	Aschenbrenner, J.C.,Saini, M.,Chopra, A.,Marples, P.G.,Balcomb, B.H.,Lithgo, R.M.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E. (deposition date: 2025-03-06, release date: 2025-04-02)
Primary citation	Aschenbrenner, J.C.,Saini, M.,Chopra, A.,Marples, P.G.,Balcomb, B.H.,Lithgo, R.M.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E. Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 To Be Published,
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation