7HKU

Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 -- Crystal structure of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 in complex with Z291279160 (DNV2_NS5A-x0741)

Summary for 7HKU

Entry DOI	10.2210/pdb7hku/pdb
Group deposition	Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 (G_1002317)
Descriptor	Genome polyprotein, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (9 entities in total)
Functional Keywords	diamond light source, rutgers university, i04-1, readdi, dengue virus, crystallographic fragment screening, pandda, xchemexplorer, viral protein
Biological source	dengue virus type 2
Total number of polymer chains	1
Total formula weight	75124.31
Authors	Saini, M.,Chopra, A.,Aschenbrenner, J.C.,Marples, P.G.,Balcomb, B.H.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E. (deposition date: 2024-10-15, release date: 2024-10-30)
Primary citation	Saini, M.,Chopra, A.,Aschenbrenner, J.C.,Marples, P.G.,Balcomb, B.H.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E. Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 To Be Published,
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation