7HKE

Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 -- Crystal structure of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 in complex with Z53860899 (DNV2_NS5A-x0174)

Summary for 7HKE

• Entry DOI: 10.2210/pdb7hke/pdb
• Group deposition: Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 (G_1002317)
• Descriptor: Genome polyprotein, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (8 entities in total)
• Functional Keywords: diamond light source, rutgers university, i04-1, readdi, dengue virus, crystallographic fragment screening, pandda, xchemexplorer, viral protein
• Biological source: dengue virus type 2
• Total number of polymer chains: 1
• Total formula weight: 75202.04

Authors

Saini, M.,Chopra, A.,Aschenbrenner, J.C.,Marples, P.G.,Balcomb, B.H.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E. (deposition date: 2024-10-15, release date: 2024-10-30, Last modification date: 2026-02-18)

• Primary citation: Saini, M.,Chopra, A.,Aschenbrenner, J.C.,Marples, P.G.,Balcomb, B.H.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E.; Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.64 Å)