7HIL

Group deposition of Chikungunya virus nsP3 macrodomain in complex with inhibitors from the READDI-AC AViDD center -- Crystal structure of Chikungunya virus nsP3 macrodomain in complex with RA-0188488-01 (CHIKV_MacB-x2129)

This is a non-PDB format compatible entry.

Summary for 7HIL

• Entry DOI: 10.2210/pdb7hil/pdb
• Group deposition: Group deposition of Chikungunya virus nsP3 macrodomain in complex with inhibitors from the READDI-AC AViDD center (G_1002314)
• Descriptor: Non-structural protein 3, DIMETHYL SULFOXIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (6 entities in total)
• Functional Keywords: diamond light source, i04-1, readdi, avidd, chikungunya virus, crystallographic fragment screening, pandda, xchemexplorer, viral protein
• Biological source: Chikungunya virus
• Total number of polymer chains: 4
• Total formula weight: 74324.48

Authors

Aschenbrenner, J.C.,Fairhead, M.,Godoy, A.S.,Almahli, H.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Chen, W.,Golding, M.,Koekemoer, L.,Lithgo, R.M.,Marples, P.G.,Ni, X.,Saleem, R.S.Z.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Todd, M.H.,Fearon, D.,von Delft, F. (deposition date: 2024-10-04, release date: 2024-10-16)

• Primary citation: Aschenbrenner, J.C.,Fairhead, M.,Godoy, A.S.,Almahli, H.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Chen, W.,Golding, M.,Koekemoer, L.,Lithgo, R.M.,Marples, P.G.,Ni, X.,Saleem, R.S.Z.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Todd, M.H.,Fearon, D.,von Delft, F.; Group deposition of Chikungunya virus nsP3 macrodomain in complex with inhibitors from the READDI-AC AViDD center; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)