7H6H

THE 1.94 A CRYSTAL STRUCTURE OF HUMAN CATHEPSIN G IN COMPLEX WITH 1-[(7-fluoronaphthalen-1-yl)methyl]-3-[[methoxycarbonyl(methyl)amino]methyl]indole-2-carboxylic acid

This is a non-PDB format compatible entry.

Summary for 7H6H

• Entry DOI: 10.2210/pdb7h6h/pdb
• Group deposition: A set of chymase crystal structures for D3R plus two CatG off-target structures (G_1002292)
• Descriptor: Cathepsin G, ZINC ION, 1-[(7-fluoronaphthalen-1-yl)methyl]-3-{[(methoxycarbonyl)(methyl)amino]methyl}-1H-indole-2-carboxylic acid, ... (5 entities in total)
• Functional Keywords: human cathepsin g, serine proteinase, complex (serine protease-inhibitor) complex, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 27479.76

Authors

Banner, D.W.,Benz, J.M.,Schlatter, D.,Hilpert, H. (deposition date: 2024-04-19, release date: 2025-03-05)

• Primary citation: Markus, R.,Tosstorff, A.; Crystal structures of human Chymase and Cathepsin G; To be published,

Experimental method

X-RAY DIFFRACTION (1.94 Å)