7H6E

THE 2.0 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH 5-fluoro-3-methyl-N-(2-methylsulfonyl-4-pyridin-4-ylphenyl)-1-benzothiophene-2-sulfonamide

This is a non-PDB format compatible entry.

Summary for 7H6E

• Entry DOI: 10.2210/pdb7h6e/pdb
• Group deposition: A set of chymase crystal structures for D3R plus two CatG off-target structures (G_1002292)
• Descriptor: Chymase, ZINC ION, 5-fluoro-N-[2-(methanesulfonyl)-4-(pyridin-4-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide, ... (4 entities in total)
• Functional Keywords: human chymase, serine proteinase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 25574.88

Authors

Banner, D.W.,Benz, J.M.,Schlatter, D.,Hilpert, H. (deposition date: 2024-04-19, release date: 2025-03-05)

• Primary citation: Markus, R.,Tosstorff, A.; Crystal structures of human Chymase and Cathepsin G; To be published,

Experimental method

X-RAY DIFFRACTION (2 Å)