7H66

THE 1.13 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH 3-hydroxy-4-methyl-2-[naphthalen-2-yl(phenyl)methyl]-4-phenylcyclobut-2-en-1-one

This is a non-PDB format compatible entry.

Summary for 7H66

• Entry DOI: 10.2210/pdb7h66/pdb
• Group deposition: A set of chymase crystal structures for D3R plus two CatG off-target structures (G_1002292)
• Descriptor: Chymase, ZINC ION, (4S)-3-hydroxy-4-methyl-2-[(S)-(naphthalen-2-yl)(phenyl)methyl]-4-phenylcyclobut-2-en-1-one, ... (4 entities in total)
• Functional Keywords: human chymase, serine proteinase, chymase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 25488.79

Authors

Banner, D.W.,Benz, J.M.,Schlatter, D.,Hilpert, H. (deposition date: 2024-04-19, release date: 2025-03-05)

• Primary citation: Markus, R.,Tosstorff, A.; Crystal structures of human Chymase and Cathepsin G; To be published,

Experimental method

X-RAY DIFFRACTION (1.13 Å)