7GUC

PanDDA analysis group deposition of ground-state model of PTP1B, using pre-clustering, cluster20

Summary for 7GUC

• Entry DOI: 10.2210/pdb7guc/pdb
• Group deposition: PanDDA analysis group deposition of ground-state model (G_1002285)
• Descriptor: Tyrosine-protein phosphatase non-receptor type 1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• Functional Keywords: pandda, diamond i04-1 fragment screening, protein tyrosine phosphatase, ptp, protein tyrosine phosphatase 1b, ptp1b, enzyme, allostery, multiconformer, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37467.70

Authors

Mehlman, T.,Ginn, H.M.,Keedy, D.A. (deposition date: 2024-01-05, release date: 2024-01-31)

• Primary citation: Mehlman, T.,Ginn, H.M.,Keedy, D.A.; PanDDA analysis group deposition of ground-state model; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.78 Å)