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7G8J

ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1216861874

Summary for 7G8J
Entry DOI10.2210/pdb7g8j/pdb
Group depositionARHGEF2 PanDDA analysis group deposition (G_1002269)
DescriptorTransforming protein RhoA, Rho guanine nucleotide exchange factor 2, 5-(difluoromethoxy)pyridin-2(3H)-one, ... (6 entities in total)
Functional Keywordssgc - diamond i04-1 fragment screening, pandda, xchemexplorer, cytosolic protein
Biological sourceHomo sapiens (human)
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Total number of polymer chains2
Total formula weight50411.96
Authors
Bradshaw, W.J.,Katis, V.L.,Bountra, C.,von Delft, F.,Brennan, P.E. (deposition date: 2023-06-22, release date: 2023-07-12)
Primary citationBradshaw, W.J.,Katis, V.L.,Bountra, C.,von Delft, F.,Brennan, P.E.
ARHGEF2 PanDDA analysis group deposition
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.986 Å)
Structure validation

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