7FZB

Crystal Structure of human FABP4 in complex with 2-[5-methyl-2-(1-methylcyclohexyl)-1,3-oxazol-4-yl]acetic acid, i.e. SMILES C1(=NC(=C(O1)C)CC(=O)O)C1(CCCCC1)C with IC50=2.9 microM

Summary for 7FZB

• Entry DOI: 10.2210/pdb7fzb/pdb
• Group deposition: To be published (G_1002264)
• Descriptor: Fatty acid-binding protein, adipocyte, [5-methyl-2-(1-methylcyclohexyl)-1,3-oxazol-4-yl]acetic acid, FORMIC ACID, ... (5 entities in total)
• Functional Keywords: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 15497.62

Authors

Ehler, A.,Benz, J.,Obst, U.,Fischer, U.,Rudolph, M.G. (deposition date: 2023-04-27, release date: 2023-06-14, Last modification date: 2024-11-20)

• Primary citation: Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human FABP4 complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.08 Å)