7FXP

Crystal Structure of human FABP4 in complex with (Z)-4-(4-bromo-2-chloroanilino)-4-oxobut-2-enoic acid, i.e. SMILES c1(c(cc(cc1)Br)Cl)NC(=O)/C=C\C(=O)O with IC50=3.4 microM

Summary for 7FXP

• Entry DOI: 10.2210/pdb7fxp/pdb
• Group deposition: To be published (G_1002264)
• Descriptor: Fatty acid-binding protein, adipocyte, SULFATE ION, (2Z)-4-(4-bromo-2-chloroanilino)-4-oxobut-2-enoic acid, ... (6 entities in total)
• Functional Keywords: fatty acid binding protein, lipid binding protein, transport, human fabp4, inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 15632.41

Authors

Ehler, A.,Benz, J.,Obst, U.,Diratsouian, J.,Rudolph, M.G. (deposition date: 2023-04-27, release date: 2023-06-14, Last modification date: 2024-11-20)

• Primary citation: Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human FABP4 complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.05 Å)