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7FWJ

Crystal Structure of human FABP4 in complex with 5-cyclohexyl-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)pyridine-3-carboxylic acid, i.e. SMILES c1(c(nc(c(c1)C(=O)O)C(F)(F)F)OCC(F)(F)F)C1CCCCC1 with IC50=0.0345135 microM

Summary for 7FWJ
Entry DOI10.2210/pdb7fwj/pdb
Group depositionTo be published (G_1002264)
DescriptorFatty acid-binding protein, adipocyte, SULFATE ION, 5-cyclohexyl-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)pyridine-3-carboxylic acid, ... (6 entities in total)
Functional Keywordslipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight15944.13
Authors
Ehler, A.,Benz, J.,Obst, U.,Richter, H.,Rudolph, M.G. (deposition date: 2023-04-27, release date: 2023-06-14, Last modification date: 2024-11-20)
Primary citationObst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.
Crystal Structure of a human FABP4 complex
To be published,
Experimental method
X-RAY DIFFRACTION (1.08 Å)
Structure validation

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PDB entries from 2024-11-20

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