7FWJ
Crystal Structure of human FABP4 in complex with 5-cyclohexyl-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)pyridine-3-carboxylic acid, i.e. SMILES c1(c(nc(c(c1)C(=O)O)C(F)(F)F)OCC(F)(F)F)C1CCCCC1 with IC50=0.0345135 microM
Summary for 7FWJ
Entry DOI | 10.2210/pdb7fwj/pdb |
Group deposition | To be published (G_1002264) |
Descriptor | Fatty acid-binding protein, adipocyte, SULFATE ION, 5-cyclohexyl-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)pyridine-3-carboxylic acid, ... (6 entities in total) |
Functional Keywords | lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 15944.13 |
Authors | Ehler, A.,Benz, J.,Obst, U.,Richter, H.,Rudolph, M.G. (deposition date: 2023-04-27, release date: 2023-06-14, Last modification date: 2024-11-20) |
Primary citation | Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G. Crystal Structure of a human FABP4 complex To be published, |
Experimental method | X-RAY DIFFRACTION (1.08 Å) |
Structure validation
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