7FH0
Crystallographic structure of two neutralizing nanobodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
Summary for 7FH0
Entry DOI | 10.2210/pdb7fh0/pdb |
Descriptor | Spike protein S1,Spike protein S1, nanobodies aRBD-2-7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | sars-cov-2, rbd, spike, nanobodies, antiviral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 3 |
Total formula weight | 106711.27 |
Authors | |
Primary citation | Ma, H.,Zhang, X.,Zheng, P.,Dube, P.H.,Zeng, W.,Chen, S.,Cheng, Q.,Yang, Y.,Wu, Y.,Zhou, J.,Hu, X.,Xiang, Y.,Zhang, H.,Chiu, S.,Jin, T. Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron. Cell Res., 32:831-842, 2022 Cited by PubMed: 35906408DOI: 10.1038/s41422-022-00700-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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