7FGL

The complex structure of PHF core domain peptide of tau, VQIVYK, and antibody's Fab domain.

Summary for 7FGL

• Entry DOI: 10.2210/pdb7fgl/pdb
• Related: 6LRA
• Descriptor: Fab Heavy Chain, Fab Light Chain, VQIVYK, ... (6 entities in total)
• Functional Keywords: tauopathies, tau protein, antibody, alzheimer's disease, fab domain, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 3
• Total formula weight: 47908.37

Authors

Tsuchida, T.,Tsuchiya, T.,Miyamoto, K.,In, Y.,Minoura, K.,Taniguchi, T.,Ishida, T.,Tomoo, K. (deposition date: 2021-07-27, release date: 2022-07-27, Last modification date: 2023-11-29)

• Primary citation: Tomohiro, T.,Takahiro, T.,Katsushiro, M.,Yasuko, I.,Katsuhiko, M.,Taizo, T.,Toshimitsu, I.,Koji, T.; The cross-reaction complex structure with VQIVYK of tau and the antibody's Fab domain.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)