7FEE
Crystal structure of the allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1
Summary for 7FEE
Entry DOI | 10.2210/pdb7fee/pdb |
Descriptor | Cannabinoid receptor 1,GlgA glycogen synthase, CHOLESTEROL, 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, ... (9 entities in total) |
Functional Keywords | signal protein, membrane protein, gpcr |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 67500.21 |
Authors | |
Primary citation | Yang, X.,Wang, X.,Xu, Z.,Wu, C.,Zhou, Y.,Wang, Y.,Lin, G.,Li, K.,Wu, M.,Xia, A.,Liu, J.,Cheng, L.,Zou, J.,Yan, W.,Shao, Z.,Yang, S. Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1. Nat.Chem.Biol., 18:831-840, 2022 Cited by PubMed: 35637350DOI: 10.1038/s41589-022-01038-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report